WebMay 1, 2000 · Eleutherobin displayed cross-resistance in multidrug resistant cell lines, an effect that was reversible by verapamil, suggesting that eleutherobin is a substrate of P-glycoprotein . Although there are no clinical data available to date on the therapeutic activity of these new antimitotic agents, it is their distinct chemical structures and ... WebSep 25, 2024 · ELTRUN is the E-Business Research Center of the Athens University of Economics and Business (AUEB) and belongs to the Department of Management …
Eleutherobin, a Novel Cytotoxic Agent That Induces Tubulin ...
WebNov 19, 2004 · Keywords: Eleutherobin, cytotoxic, Tubulin polymerization, asymmetric dihydroxylation, Lindlar’s catalyst Introduction The Eleuthesides comprise a family of marine derived natural products that exhibit cytotoxic activity.1 Most intriguing of these is Eleutherobin 1, which was isolated in 1995 by Fenical et al., from an Eleutherobia … WebSep 1, 2000 · Z -Eleutherobin ( 7) is a geometric isomer of eleutherobin at the C-2′ to C-3′ double bond of the C-8 N - (6′)-methylurocanic acid ester side chain. Desmethyleleutherobin ( 8) differs from eleutherobin by the presence of a hydroxyl instead of a methoxyl at C-4. blouse with a sailor collar
Structure-activity profiles of eleutherobin analogs and ... - Springer
WebMar 15, 1998 · Eleutherobin is a novel natural product isolated from a marine soft coral that is extremely potent for inducing tubulin polymerization in vitro and is cytotoxic for cancer cells with an IC50... WebEleutherobin is a potent β-microtubule inhibitor with an IC50 value of 2 μM. Eleutherobin can be isolated from a marine soft coral. Eleutherobin has cytotoxic activity against … WebApr 6, 2024 · Congrats Dr Paul Scesa, Elucidating and engineering eleutherobin biosynthesis grant. Read More. News. Apr 07, 2024. Dr. Amy Barrios was named the “Outstanding Undergraduate Research Mentor” for the College of Pharmacy (2024) Read More. News. Apr 06, 2024. BRAXTEN HORNSBY RECIPIENT OF A BEST POSTER … blouse with inside tank top