Deuterated arachidonic acidd5
WebDec 19, 2012 · A deuterated substrate analogue, 3,3,4,4-norcarane-d(4), afforded drastically reduced amounts of C3 alcohol (8%) and desaturation products (5%), while the radical rearranged alcohol was now the ... WebFeb 28, 2014 · Conversion of arachidonic acid to prostaglandin G2/H2 catalyzed by prostaglandin H synthase (PGHS) is proposed to involve initial transfer of the C13 pro-(S) hydrogen atom from arachidonate to the Tyr385 radical in PGHS, followed by insertion of two oxygen molecules and several chemical bond rearrangements. The initial hydrogen …
Deuterated arachidonic acidd5
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WebJan 1, 2000 · In vivo elongation/desaturation of deuterated d5-linoleic acid (d5-LA) to form arachidonic acid (AA), and d5-α-linolenic acid (d5-LNA) to form docosahexaenoic acid (DHA), was studied in 19 ... WebArachidonic acid-d5 is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by GC- or LC-MS. …
WebArachidonic acid is transformed in vivo to a wide variety of oxygenated metabolites. The limiting factor in the quantitation of these metabolites by GC/MS using selected ion monitoring (SIM) is the availability of suitable stable-isotope labelled internal standards. ... Dive into the research topics of 'Preparation of deuterated arachidonic ... WebArachidonic acid-d 5 is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes. Stable heavy isotopes of …
WebThe arachidonic acid Quant-PAK has been designed for the convenient, precise quantification of arachidonic acid by GC- or LC-MS. It includes a 50 µg vi... 您好,欢迎光临欣博盛生物科技商城! WebMar 31, 2024 · Arachidonic acid (ARA) is a major component of lipid bilayers as well as the key substrate for the eicosanoid cascades. ARA is readily oxidized, and its non …
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WebDec 15, 2024 · In this study we analyzed the relative activity of human recombinant enzymes COX-2, 5-LOX, and 15-LOX-2 using a library of arachidonic acids variably deuterated at the bis-allylic (C7, C10, and ... trotec guide to laser beam alignmentWebIsotope sensitive branching and kinetic isotope effects in the reaction of deuterated arachidonic acids with human 12- and 15-lipoxygenases. / Jacquot, Cyril; Wecksler, Aaron T.; McGinley, Chris M. et al. In: Biochemistry, Vol. 47, No. 27, 08.07.2008, p. 7295-7303. Research output: Contribution to journal › Article › peer-review trotec heizlüfter tfc 2 eWeb14:0 PA-d54 (327178-99-4) is a deuterated phosphatidic acid, in which 54 protons of dimyristoyl are replaced by deuterium isotope. Store at −20°C. Order online. GB EN. Applications Products Services Support. ... arachidonic acid-d11. Avanti Polar Lipids 861810E, ethanol solution. View Price and Availability. Avanti. 860673P. C18:1 Glucosyl ... trotec hepa filter