Cst plin2

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August undefined, 2024

WebSep 13, 2024 · Myelin uptake increases PLIN2 expression in macrophages in a PPARγ-dependent manner. Demyelinating lesions are characterized by the abundant presence of foamy macrophages loaded with cholesterol-containing LDs [].As PLIN2 is the main LD-associated protein on cholesterol-containing LDs and given its key role in LD biology [], … WebFeb 6, 2013 · Subscribe to downloadDust 2 Control [CP Example] Subscribe. Description. …

Perilipin 2 and lipid droplets provide reciprocal stabilization

WebGene target information for PLIN2 - perilipin 2 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebNational Center for Biotechnology Information ear hurts when i blow nose

Recombinant Rabbit monoclonal [EPR3713] to Perilipin-2 …

WebMay 15, 2014 · Background Perilipin 2 (Plin2) is a lipid droplet protein that has roles in both lipid and glucose homeostasis. An increase in Plin2 in liver is associated with the development of steatosis, glucose intolerance, and … WebNov 18, 2014 · Although perilipin 2 (Plin2) has been shown to bind lipids with high affinity, the Plin2 lipid binding site has yet to be defined. This is of interest since Plin2's affinity for lipids has been suggested to be important for lipid droplet biogenesis and intracellular triacylglycerol accumulation. To define these regions, mouse Plin2 and several ... WebDec 13, 2024 · For example, PLIN2 and PLIN3 expression predominates in mouse liver, muscle cells , and pancreatic islets , whereas PLIN1 is significantly upregulated as preadipocytes mature into adipocytes . Perilipin protein function has been studied primarily in rodents, and, for example, PLIN2 ( 17 , 18 ) or PLIN3 ( 19 ) null mice are protected … css display flex 換行

Lipid Droplet Accumulation in Human Pancreatic Islets Is …

Cst plin2

Accurate liquid biopsy for the diagnosis of non-alcoholic ... - Gut

WebPLIN2 is an inherent perilipin protein, and its expression and phosphorylation are involved in lipolysis, lipophagy, lipid droplet fusion, and signal transduction. 49–52 PLIN2 activation-mediated LDs accumulation was observed in microglia activated by various inflammatory stimuli, which was closely related to the production of ROS and ... WebJul 3, 2024 · Of the corresponding gene products, PLIN2 is the only constitutive and …

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WebFeb 8, 2024 · RDH/CG2064 interacts with the lipid droplet-resident protein Plin2 and the RDH/CG2064-Plin2 axis acts to reduce the overall level and lipid droplet localization of Bmm/ATGL lipase. This axis is important for larval survival under prolonged starvation. Thus, we discovered an RDH-Plin2 axis modulates lipid droplet size. WebJun 16, 2024 · plin2 Background Perilipin-2/Plin-2, also known as adipose differentiation-related protein (ADFP), ADRP, and adipophilin, is a …

WebJan 19, 2024 · PLIN2 expression goes up when β cells are exposed to a lipid load or to … Polyclonal Antibody for studying perilipin 2. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, Perilipin-2 Antibody (CST #45535) is ready to ship.

WebJun 16, 2016 · Twenty microgram of protein was analyzed by western blot with antibodies against PLIN2 (Proteintech) and ACTIN (CST). HRP coupled secondary antibodies were obtained from Abcam. Chemiluminescence … WebMonoclonal Antibody for studying perilipin. Cited in 227 publications. Validated for WB, IP, IHC, IF, IF. Available in 2 sizes. Highly specific and …

WebResults The algorithm for NASH using PLIN2 mean florescence intensity (MFI) combined with waist circumference, triglyceride, alanine aminotransferase (ALT) and presence/absence of diabetes as covariates had an accuracy of 93% in the discovery cohort and of 92% in the validation cohort. Sensitivity and specificity were 95% and 90% in the …

WebPerilipin-2/Plin-2, also known as adipose differentiation-related protein (ADFP), ADRP, and adipophilin, is a member of the perilipin family of lipid droplet (LD) proteins that functions in lipid accumulation, lipid storage, … ear hurts when i chewWebExam Information. To become certified as a CST (Certified Service Technician®), you … css display flex 间距WebAug 28, 2024 · Here, we develop a set of genome-edited PLIN2 reporter cell lines that … css display flex 靠右WebMar 29, 2024 · The PLIN2-intramuscular triglyceride association was reduced postexercise. PLIN2-PLIN5 proteins were all more abundant in women than in men (p = 0.037 and p < 0.0001, respectively), consistent with higher intramyocellular lipid content observed in female skeletal muscle. High PLIN2 protein level is associated with colorectal cancer. css display flow-rootWebMay 6, 2024 · A recent report shows that cardiac overexpression of Plin2 result in massive myocardial steatosis suggesting that Plin2 stabilizes LDs. In this study, we hypothesized that deficiency in Plin2 ... ear hurts when i open my jawWebPLIN2 knockdown in the RVLM blocked the number of iNOS + and PCNA + microglia, … css display footer at bottomWebApr 28, 2024 · Moreover, PLIN2 knockout mice are resistant to diet-induced obesity, fatty liver disease and alcohol-induced steatosis, suggesting that PLIN2 is responsible for lipid accumulation, particularly in the liver [41, 42]. Taken together, these studies suggest that PLIN2 promotes LD formation and thereby protects TG from lipolysis. css display flow