Collagen IV (ColIV or Col4) is a type of collagen found primarily in the basal lamina. The collagen IV C4 domain at the C-terminus is not removed in post-translational processing, and the fibers link head-to-head, rather than in parallel. Also, collagen IV lacks the regular glycine in every third residue necessary for the tight, collagen helix. This makes the overall arrangement more sloppy with kinks. These two features cause the collagen to form in a sheet, the form of the basal lamin… WebThe main five types of collagen and what they do are: Type I. This type makes up 90% of your body’s collagen. Type I is densely packed and used to provide structure to your …
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WebAddgene now distributes ready-to-use recombinant antibodies. Browse our growing collection and learn more about our antibody production process, quality control, and … WebCOL3A1 Addgene Alerts Receive email alerts when new plasmids with this gene become available. Log in to subscribe to Addgene Alerts. Description collagen, type III, alpha 1 Also known as Species Gallus gallus Entrez ID 396340 Plasmids containing this gene, or a homologous gene. Showing 1 to 1 of 1 entries Show entries Search table: Previous 1 buckeye auto mall shelby ohio
COL4A4 gene: MedlinePlus Genetics
WebJan 22, 2024 · Characterization by high-resolution crystal structure analysis of a triple-helix region of human collagen type III with potent cell adhesion activity. Biochem Biophys … WebApr 15, 2024 · The glomerular basement membrane (GBM) is a critical component of the kidney’s blood filtration barrier. Alport syndrome, a hereditary disease leading to kidney failure, is caused by the loss or dysfunction of the GBM’s major collagen type IV (COL4) isoform α3α4α5. The constituent COL4 α-chains assemble into heterotrimers in the … WebThe type IV collagen C4 domain at the C-terminus is not removed in post-translational processing, and the fibers are thus link head-to-head, rather than in a parallel fashion. Also, type IV collagen lacks a glycine in every third amino-acid residue necessary for the tight collagen helix. Thus, the overall collagen-IV conformation is ... buckeye automotive group